After playing it all week I can only pick out one issue which I think the police seem to be straight on you regardless of how many people saw you do a crime, it'd be nice if they were a bit smarter and only went off information they have.
For example you silently take out some dude while no one is around. So while you're walking away, someone found the body and the police are searching the area, but they're not specifically searching for you.
Kill someone in front of another person? They need to call it in. At the minute it feels like every ped is wearing google glasses that are linked up to the LSPD database.